Mary Gates Endowment For Students

Home Blood Collection and Stabilization

Faculty PI Name:

Ashleigh Theberge, Ph.D.

Project or Start-Up Company Name:

Home Blood Collection and Stabilization

Lab/Project Website:

https://depts.washington.edu/bcmelab/pilotstudy/

Work Location:

Department of Chemistry, Bagley Hall

Work Hours (include times of recurring group meetings, special events, etc.):

  • This is a full-time internship; specific hours and experiments will be determined on a weekly basis in coordination with the intern and other team members.
  • Weekly group meetings on Tuesdays from 1-2:30pm

Overall Program Goal:

Our lab has developed an at-home blood collection and stabilization kit (homeRNA) that enables people to collect their own blood at home, to be mailed back to the lab for transcriptomics analysis. We have validated our homeRNA kit in a pilot study with ~50 users. This internship will expand our capabilities to other analytes of interest for clinical applications (beyond RNA). The technology is of great interest to pharmaceutical companies and healthcare, with a strong potential to improve clinical trials and guide patient-specific therapy decisions. In addition to product development, this internship will evaluate potential markets for our technology, guiding experimental design to enable market-focused data collection.

Intern Project Description and Responsibilities:

The intern will work on methods to stabilize analytes in blood. The intern will conduct literature reviews to plan experiments and understand market needs, conduct wet-lab experiments, analyze their results, and present their findings in oral presentations and written reports.

Pre-requisites:

Skills required include biochemistry techniques (dilutions, pipetting, sterile technique), familiarity with blood samples and human specimens, and the ability to design and execute experiments independently.

Level of Independence:

The intern will have independence to plan, execute, and analyze their own experiments. They will be responsible for setting short-term and long-term goals in collaboration with the PI (Prof. Theberge) and a senior graduate student, who will serve as the primary daily point of contact and mentor.

Learning Opportunities:

  • Learn how to survey the literature for prior methods of relevance and market needs. Plan future experiments based on literature review.
  • Execute and analyze experimental results. Modify and troubleshoot to achieve long-term project goals.
  • Communicate results in oral presentations and written reports.